Clustering by genetic ancestry using genome-wide SNP data

BACKGROUND: Population stratification can cause spurious associations in a genome-wide association study (GWAS), and occurs when differences in allele frequencies of single nucleotide polymorphisms (SNPs) are due to ancestral differences between cases and controls rather than the trait of interest....

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Hlavní autoři: Solovieff, Nadia, Hartley, Stephen W, Baldwin, Clinton T, Perls, Thomas T, Steinberg, Martin H, Sebastiani, Paola
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2010
Témata:
Methodology Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3018397/
https://ncbi.nlm.nih.gov/pubmed/21143920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-11-108
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