Clustering by genetic ancestry using genome-wide SNP data

BACKGROUND: Population stratification can cause spurious associations in a genome-wide association study (GWAS), and occurs when differences in allele frequencies of single nucleotide polymorphisms (SNPs) are due to ancestral differences between cases and controls rather than the trait of interest....

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Bibliografiske detaljer
Main Authors: Solovieff, Nadia, Hartley, Stephen W, Baldwin, Clinton T, Perls, Thomas T, Steinberg, Martin H, Sebastiani, Paola
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Methodology Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3018397/
https://ncbi.nlm.nih.gov/pubmed/21143920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-11-108
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