Genetic modifiers of the severity of sickle cell anemia identified through a genome-wide association study

We conducted a genome-wide association study (GWAS) to discover single nucleotide polymorphisms (SNPs) associated with the severity of sickle cell anemia in 1,265 patients with either “severe” or “mild” disease based on a network model of disease severity. We analyzed data using single SNP analysis...

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Detalhes bibliográficos
Main Authors: Sebastiani, Paola, Solovieff, Nadia, Hartley, Stephen W., Milton, Jacqueline N., Riva, Alberto, Dworkis, Daniel A., Melista, Efthymia, Klings, Elizabeth S., Garrett, Melanie E., Telen, Marilyn J., Ashley-Koch, Allison, Baldwin, Clinton T., Steinberg, Martin H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903007/
https://ncbi.nlm.nih.gov/pubmed/20029952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajh.21572
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