A Genome-Wide Association Study of Total Bilirubin and Cholelithiasis Risk in Sickle Cell Anemia

Serum bilirubin levels have been associated with polymorphisms in the UGT1A1 promoter in normal populations and in patients with hemolytic anemias, including sickle cell anemia. When hemolysis occurs circulating heme increases, leading to elevated bilirubin levels and an increased incidence of chole...

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Bibliografski detalji
Glavni autori: Milton, Jacqueline N., Sebastiani, Paola, Solovieff, Nadia, Hartley, Stephen W., Bhatnagar, Pallav, Arking, Dan E., Dworkis, Daniel A., Casella, James F., Barron-Casella, Emily, Bean, Christopher J., Hooper, W. Craig, DeBaun, Michael R., Garrett, Melanie E., Soldano, Karen, Telen, Marilyn J., Ashley-Koch, Allison, Gladwin, Mark T., Baldwin, Clinton T., Steinberg, Martin H., Klings, Elizabeth S.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338756/
https://ncbi.nlm.nih.gov/pubmed/22558097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034741
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