Clustering by genetic ancestry using genome-wide SNP data

BACKGROUND: Population stratification can cause spurious associations in a genome-wide association study (GWAS), and occurs when differences in allele frequencies of single nucleotide polymorphisms (SNPs) are due to ancestral differences between cases and controls rather than the trait of interest....

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Hauptverfasser: Solovieff, Nadia, Hartley, Stephen W, Baldwin, Clinton T, Perls, Thomas T, Steinberg, Martin H, Sebastiani, Paola
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2010
Schlagworte:
Methodology Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3018397/
https://ncbi.nlm.nih.gov/pubmed/21143920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-11-108
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