A novel test for gene-ancestry interactions in genome-wide association data.

Genome-wide association study (GWAS) data on a disease are increasingly available from multiple related populations. In this scenario, meta-analyses can improve power to detect homogeneous genetic associations, but if there exist ancestry-specific effects, via interactions on genetic background or w...

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Hlavní autoři: Joanna L Davies, Jean-Baptiste Cazier, Malcolm G Dunlop, Richard S Houlston, Ian P Tomlinson, Chris C Holmes
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2012-01-01
Edice:PLoS ONE
On-line přístup:http://europepmc.org/articles/PMC3516524?pdf=render
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