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Epigenetics as a Therapeutic Target in Breast Cancer
Epigenetics refers to alterations in gene expression due to modifications in histone acetylation and DNA methylation at the promoter regions of genes. Unlike genetic mutations, epigenetic alterations are not due to modifications in the gene primary nucleotide sequence. The importance of epigenetics...
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主要な著者: | , |
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フォーマット: | Artigo |
言語: | Inglês |
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2012
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オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3515719/ https://ncbi.nlm.nih.gov/pubmed/22836913 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10911-012-9263-3 |
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