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Epigenetics as a Therapeutic Target in Breast Cancer

Epigenetics refers to alterations in gene expression due to modifications in histone acetylation and DNA methylation at the promoter regions of genes. Unlike genetic mutations, epigenetic alterations are not due to modifications in the gene primary nucleotide sequence. The importance of epigenetics...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Connolly, Roisin, Stearns, Vered
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3515719/
https://ncbi.nlm.nih.gov/pubmed/22836913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10911-012-9263-3
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