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Nicotinic α4β2 receptor imaging agents. Part IV. Synthesis and Biological Evaluation of 3-(2-(S)-3,4-dehydropyrrolinylmethoxy)-5-(3’-(18)F-Fluoropropyl)pyridine ((18)F-Nifrolene) using PET
Imaging agents for nicotinic α4β2 receptors in the brain have been underway for studying various CNS disorders. Previous studies from our laboratories have reported the successful development of agonist, (18)F-nifene. In attempts to develop potential antagonists, (18)F-nifrolidine and (18)F-nifzetid...
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| Autors principals: | , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3514651/ https://ncbi.nlm.nih.gov/pubmed/23141552 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2012.09.009 |
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