Nicotinic α4β2 Receptor Imaging Agents. Part III. Synthesis and Biological Evaluation of 3-(2-(S)-Azetidinylmethoxy)-5-(3′-(18)F-Fluoropropyl)Pyridine ((18)F-Nifzetidine)

Thalamic and extrathalamic nicotinic α4β2 receptors found in the brain have been implicated in Alzheimer’s disease, Parkinson’s disease, substance abuse and other disorders. We report here the development of 3-(2-(S)-azetidinylmethoxy)-5-(3′-fluoropropyl)pyridine (nifzetidine) as a new putative high...

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Detalhes bibliográficos
Main Authors: Pichika, Rama, Easwaramoorthy, Balu, Christian, Bradley T., Shi, Bingzhi, Narayanan, Tanjore K., Collins, Daphne, Mukherjee, Jogeshwar
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3217100/
https://ncbi.nlm.nih.gov/pubmed/21831652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2011.05.005
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