Klucel™ EF and ELF polymers for immediate-release oral dosage forms prepared by melt extrusion technology

The objective of this research work was to evaluate Klucel™ hydroxypropylcellulose (HPC) EF and ELF polymers, for solubility enhancement as well as to address some of the disadvantages associated with solid dispersions. Ketoprofen (KPR), a Biopharmaceutics Classification System class II drug with po...

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Detalhes bibliográficos
Main Authors: Mohammed, Noorullah Naqvi, Majumdar, Soumyajit, Singh, Abhilasha, Deng, Weibin, Murthy, Narasimha S., Pinto, Elanor, Tewari, Divya, Durig, Thomas, Repka, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3513444/
https://ncbi.nlm.nih.gov/pubmed/22961411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-012-9834-z
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