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Practical Method for the Cu-Mediated Trifluoromethylation of Arylboronic Acids with CF(3) Radicals Derived from NaSO(2)CF(3) and tert-Butyl Hydroperoxide (TBHP)

[Image: see text] A mild and practical protocol for the copper-mediated trifluoromethylation of aryl and heteroaryl boronic acids using NaSO(2)CF(3) (Langlois’ reagent) and TBHP is described. The reaction proceeds at room temperature under ambient conditions, and the products can be readily purified...

詳細記述

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書誌詳細
主要な著者: Ye, Yingda, Künzi, Stefan A., Sanford, Melanie S.
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3513340/
https://ncbi.nlm.nih.gov/pubmed/22984900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol3022726
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