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Increased CD36 protein as a response to defective insulin signaling in macrophages
Accelerated atherosclerosis is a major cause of morbidity and death in insulin-resistant states such as obesity and the metabolic syndrome, but the underlying mechanisms are poorly understood. We show that macrophages from obese (ob/ob) mice have increased binding and uptake of oxidized LDL, in part...
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| Główni autorzy: | , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Society for Clinical Investigation
2004
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC351316/ https://ncbi.nlm.nih.gov/pubmed/14991075 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200419528 |
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