Homozygosity for an allele encoding deacetylated FoxO1 protects macrophages from cholesterol-induced inflammation without increasing apoptosis

OBJECTIVE: Insulin resistance renders macrophages more prone to cholesterol-induced apoptosis by promoting nuclear localization of transcription factor FoxO1. But FoxO1 also decreases macrophage inflammation, raising the question of how is the balance between pro-apoptotic and anti-inflammatory effe...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Tsuchiya, Kyoichiro, Banks, Alexander S., Liang, Chien-Ping, Tabas, Ira, Tall, Alan R., Accili, Domenico
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3220790/
https://ncbi.nlm.nih.gov/pubmed/21940942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.110.219477
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares