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Force Distribution Reveals Signal Transduction in E. coli Hsp90

Heat-shock protein 90 (Hsp90) is an ubiquitous chaperone that is essential for cell function in that it promotes client-protein folding and stabilization. Its function is tightly controlled by an ATP-dependent large conformational transition between the open and closed states of the Hsp90 dimer. The...

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Bibliografske podrobnosti
Main Authors: Seifert, Christian, Gräter, Frauke
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3512052/
https://ncbi.nlm.nih.gov/pubmed/23200053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.09.008
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