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Dynamic Allostery in the Methionine Repressor Revealed by Force Distribution Analysis

Many fundamental cellular processes such as gene expression are tightly regulated by protein allostery. Allosteric signal propagation from the regulatory to the active site requires long-range communication, the molecular mechanism of which remains a matter of debate. A classical example for long-ra...

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Библиографические подробности
Главные авторы: Stacklies, Wolfram, Xia, Fei, Gräter, Frauke
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2009
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2775130/
https://ncbi.nlm.nih.gov/pubmed/19936294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000574
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