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Molecular and Thermodynamic Insights into the Conformational Transitions of Hsp90

Hsp90, the most abundant cellular protein, has been implicated in numerous physiological and pathological processes. It controls protein folding and prevents aggregation, but it also plays a role in cancer and neurological disorders, making it an attractive drug target. Experimental efforts have dem...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Simunovic, Mijo, Voth, Gregory A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Biophysical Society 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3400771/
https://ncbi.nlm.nih.gov/pubmed/22853906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.06.018
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