Site-specific silencing of regulatory elements as a mechanism of X-inactivation

The inactive X chromosome’s (Xi) physical territory is microscopically devoid of transcriptional hallmarks and enriched in silencing-associated modifications. How these microscopic signatures relate to specific Xi sequence is unknown. Therefore, we profiled Xi gene expression and chromatin states at...

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Autori principali: Calabrese, J. Mauro, Sun, Wei, Song, Lingyun, Mugford, Joshua W., Williams, Lucy, Yee, Della, Starmer, Joshua, Mieczkowski, Piotr, Crawford, Gregory E., Magnuson, Terry
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511858/
https://ncbi.nlm.nih.gov/pubmed/23178118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.10.037
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