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Evidence of Xist RNA-independent initiation of mouse imprinted X-chromosome inactivation
XX female mammals undergo transcriptional silencing of most genes on one of their two X-chromosomes to equalize X-linked gene dosage with XY males in a process referred to as X-chromosome inactivation (XCI). XCI is a paradigm of epigenetic regulation1. Once enacted in individual cells of the early f...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2754729/ https://ncbi.nlm.nih.gov/pubmed/19571810 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08161 |
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