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Evidence of Xist RNA-independent initiation of mouse imprinted X-chromosome inactivation

XX female mammals undergo transcriptional silencing of most genes on one of their two X-chromosomes to equalize X-linked gene dosage with XY males in a process referred to as X-chromosome inactivation (XCI). XCI is a paradigm of epigenetic regulation1. Once enacted in individual cells of the early f...

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Detalhes bibliográficos
Main Authors: Kalantry, Sundeep, Purushothaman, Sonya, Bowen, Randall Bryant, Starmer, Joshua, Magnuson, Terry
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754729/
https://ncbi.nlm.nih.gov/pubmed/19571810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08161
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