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Evidence for Local Regulatory Control of Escape from Imprinted X Chromosome Inactivation

X chromosome inactivation (XCI) is an epigenetic process that almost completely inactivates one of two X chromosomes in somatic cells of mammalian females. A few genes are known to escape XCI and the mechanism for this escape remains unclear. Here, using mouse trophoblast stem (TS) cells, we address...

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Detalhes bibliográficos
Main Authors: Mugford, Joshua W., Starmer, Joshua, Williams, Rex L., Calabrese, J. Mauro, Mieczkowski, Piotr, Yee, Della, Magnuson, Terry
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4063926/
https://ncbi.nlm.nih.gov/pubmed/24653000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.114.162800
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