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Three periods of regulatory innovation during vertebrate evolution

The gain, loss, and modification of gene regulatory elements may underlie a significant proportion of phenotypic changes on animal lineages. To investigate the gain of regulatory elements throughout vertebrate evolution we identified genome-wide sets of putative regulatory regions for five vertebrat...

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Detalhes bibliográficos
Main Authors: Lowe, Craig B., Kellis, Manolis, Siepel, Adam, Raney, Brian J., Clamp, Michele, Salama, Sofie R., Kingsley, David M., Lindblad-Toh, Kerstin, Haussler, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511857/
https://ncbi.nlm.nih.gov/pubmed/21852499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1202702
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