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Endangered Species Hold Clues to Human Evolution

We report that 18 conserved, and by extension functional, elements in the human genome are the result of retroposon insertions that are evolving under purifying selection in mammals. We show evidence that 1 of the 18 elements regulates the expression of ASXL3 during development by encoding an altern...

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Detalhes bibliográficos
Main Authors: Lowe, Craig B., Bejerano, Gill, Salama, Sofie R., Haussler, David
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2884192/
https://ncbi.nlm.nih.gov/pubmed/20332163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jhered/esq016
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