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Endangered Species Hold Clues to Human Evolution

We report that 18 conserved, and by extension functional, elements in the human genome are the result of retroposon insertions that are evolving under purifying selection in mammals. We show evidence that 1 of the 18 elements regulates the expression of ASXL3 during development by encoding an altern...

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Bibliografische gegevens
Hoofdauteurs: Lowe, Craig B., Bejerano, Gill, Salama, Sofie R., Haussler, David
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2010
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2884192/
https://ncbi.nlm.nih.gov/pubmed/20332163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jhered/esq016
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