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Thousands of human mobile element fragments undergo strong purifying selection near developmental genes
At least 5% of the human genome predating the mammalian radiation is thought to have evolved under purifying selection, yet protein-coding and related untranslated exons occupy at most 2% of the genome. Thus, the majority of conserved and, by extension, functional sequence in the human genome seems...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2007
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1876562/ https://ncbi.nlm.nih.gov/pubmed/17463089 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611223104 |
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