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Strong Purifying Selection in Transmission of Mammalian Mitochondrial DNA

There is an intense debate concerning whether selection or demographics has been most important in shaping the sequence variation observed in modern human mitochondrial DNA (mtDNA). Purifying selection is thought to be important in shaping mtDNA sequence evolution, but the strength of this selection...

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Detalhes bibliográficos
Main Authors: Stewart, James Bruce, Freyer, Christoph, Elson, Joanna L, Wredenberg, Anna, Cansu, Zekiye, Trifunovic, Aleksandra, Larsson, Nils-Göran
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2214808/
https://ncbi.nlm.nih.gov/pubmed/18232733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0060010
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