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Strong Purifying Selection in Transmission of Mammalian Mitochondrial DNA

There is an intense debate concerning whether selection or demographics has been most important in shaping the sequence variation observed in modern human mitochondrial DNA (mtDNA). Purifying selection is thought to be important in shaping mtDNA sequence evolution, but the strength of this selection...

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Autors principals: Stewart, James Bruce, Freyer, Christoph, Elson, Joanna L, Wredenberg, Anna, Cansu, Zekiye, Trifunovic, Aleksandra, Larsson, Nils-Göran
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2214808/
https://ncbi.nlm.nih.gov/pubmed/18232733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0060010
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