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The mitochondrial RNA polymerase contributes critically to promoter specificity in mammalian cells

Initiation of transcription in mammalian mitochondria depends on three proteins: mitochondrial RNA polymerase (POLRMT), mitochondrial transcription factor A (TFAM) and mitochondrial transcription factor B2 (TFB2M). We show here that the recombinant mouse and human transcription machineries are unabl...

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Detalhes bibliográficos
Main Authors: Gaspari, Martina, Falkenberg, Maria, Larsson, Nils-Göran, Gustafsson, Claes M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC533051/
https://ncbi.nlm.nih.gov/pubmed/15526033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600465
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