Evaluating Purifying Selection in the Mitochondrial DNA of Various Mammalian Species

Mitochondrial DNA (mtDNA), the circular DNA molecule inside the mitochondria of all eukaryotic cells, has been shown to be under the effect of purifying selection in several species. Traditional testing of purifying selection has been based simply on ratios of nonsynonymous to synonymous mutations,...

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Detalhes bibliográficos
Main Authors: Soares, Pedro, Abrantes, Diogo, Rito, Teresa, Thomson, Noel, Radivojac, Predrag, Li, Biao, Macaulay, Vincent, Samuels, David C., Pereira, Luísa
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606437/
https://ncbi.nlm.nih.gov/pubmed/23533597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058993
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