Evaluating Purifying Selection in the Mitochondrial DNA of Various Mammalian Species

Mitochondrial DNA (mtDNA), the circular DNA molecule inside the mitochondria of all eukaryotic cells, has been shown to be under the effect of purifying selection in several species. Traditional testing of purifying selection has been based simply on ratios of nonsynonymous to synonymous mutations,...

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Main Authors: Soares, Pedro, Abrantes, Diogo, Rito, Teresa, Thomson, Noel, Radivojac, Predrag, Li, Biao, Macaulay, Vincent, Samuels, David C., Pereira, Luísa
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2013
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606437/
https://ncbi.nlm.nih.gov/pubmed/23533597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058993
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