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Functional Avidity: A Measure to Predict the Efficacy of Effector T Cells?

The functional avidity is determined by exposing T-cell populations in vitro to different amounts of cognate antigen. T-cells with high functional avidity respond to low antigen doses. This in vitro measure is thought to correlate well with the in vivo effector capacity of T-cells. We here present t...

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Détails bibliographiques
Auteurs principaux: Viganò, Selena, Utzschneider, Daniel T., Perreau, Matthieu, Pantaleo, Giuseppe, Zehn, Dietmar, Harari, Alexandre
Format: Artigo
Langue:Inglês
Publié: Hindawi Publishing Corporation 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511839/
https://ncbi.nlm.nih.gov/pubmed/23227083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/153863
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