Rapid Perturbation in Viremia Levels Drives Increases in Functional Avidity of HIV-specific CD8 T Cells

The factors determining the functional avidity and its relationship with the broad heterogeneity of antiviral T cell responses remain partially understood. We investigated HIV-specific CD8 T cell responses in 85 patients with primary HIV infection (PHI) or chronic (progressive and non-progressive) i...

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Main Authors: Viganò, Selena, Bellutti Enders, Felicitas, Miconnet, Isabelle, Cellerai, Cristina, Savoye, Anne-Laure, Rozot, Virginie, Perreau, Matthieu, Faouzi, Mohamed, Ohmiti, Khalid, Cavassini, Matthias, Bart, Pierre-Alexandre, Pantaleo, Giuseppe, Harari, Alexandre
格式: Artigo
語言:Inglês
出版: Public Library of Science 2013
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701695/
https://ncbi.nlm.nih.gov/pubmed/23853580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003423
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