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Distinct Profiles of Cytotoxic Granules in Memory CD8 T Cells Correlate with Function, Differentiation Stage, and Antigen Exposure

Cytotoxic CD8 T cells exert their antiviral and antitumor activity primarily through the secretion of cytotoxic granules. Degranulation activity and cytotoxic granules (perforin plus granzymes) generally define CD8 T cells with cytotoxic function. In this study, we have investigated the expression o...

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Bibliografiske detaljer
Main Authors: Harari, Alexandre, Enders, Felicitas Bellutti, Cellerai, Cristina, Bart, Pierre-Alexandre, Pantaleo, Giuseppe
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2655574/
https://ncbi.nlm.nih.gov/pubmed/19176626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02528-08
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