Skewed association of polyfunctional antigen-specific CD8 T cell populations with HLA-B genotype

We studied CD8 T cell responses against HIV-1, cytomegalovirus, Epstein–Barr virus, and influenza in 128 subjects and demonstrate that polyfunctional CD8 T cell responses, also including IL-2 production and Ag-specific proliferation, are predominantly driven by virus epitopes restricted by HLA-B all...

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Sonraí Bibleagrafaíochta
Main Authors: Harari, Alexandre, Cellerai, Cristina, Enders, Felicitas Bellutti, Köstler, Josef, Codarri, Laura, Tapia, Gonzalo, Boyman, Onur, Castro, Erika, Gaudieri, Silvana, James, Ian, John, Mina, Wagner, Ralf, Mallal, Simon, Pantaleo, Giuseppe
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2007
Ábhair:
Biological Sciences
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1999394/
https://ncbi.nlm.nih.gov/pubmed/17911249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707570104
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