Role of Histone Deacetylases in Gene Regulation at Nuclear Lamina

Theoretical models suggest that gene silencing at the nuclear periphery may involve “closing” of chromatin by transcriptional repressors, such as histone deacetylases (HDACs). Here we provide experimental evidence confirming these predictions. Histone acetylation, chromatin compactness, and gene rep...

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Detaylı Bibliyografya
Asıl Yazarlar: Milon, Beatrice C., Cheng, Haibo, Tselebrovsky, Mikhail V., Lavrov, Sergei A., Nenasheva, Valentina V., Mikhaleva, Elena A., Shevelyov, Yuri Y., Nurminsky, Dmitry I.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2012
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511463/
https://ncbi.nlm.nih.gov/pubmed/23226217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049692
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