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Role of Histone Deacetylases in Gene Regulation at Nuclear Lamina

Theoretical models suggest that gene silencing at the nuclear periphery may involve “closing” of chromatin by transcriptional repressors, such as histone deacetylases (HDACs). Here we provide experimental evidence confirming these predictions. Histone acetylation, chromatin compactness, and gene rep...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Milon, Beatrice C., Cheng, Haibo, Tselebrovsky, Mikhail V., Lavrov, Sergei A., Nenasheva, Valentina V., Mikhaleva, Elena A., Shevelyov, Yuri Y., Nurminsky, Dmitry I.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511463/
https://ncbi.nlm.nih.gov/pubmed/23226217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049692
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