Biochemical Reconstitution of Hemorrhagic-Fever Arenavirus Envelope Glycoprotein-Mediated Membrane Fusion

The membrane-anchored proteins of enveloped viruses form labile spikes on the virion surface, primed to undergo large-scale conformational changes culminating in virus-cell membrane fusion and viral entry. The prefusion form of these envelope glycoproteins thus represents an important molecular targ...

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Main Authors: Thomas, Celestine J., Shankar, Sundaresh, Casquilho-Gray, Hedi E., York, Joanne, Sprang, Stephen R., Nunberg, Jack H.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511403/
https://ncbi.nlm.nih.gov/pubmed/23226473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051114
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