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Dissection of the Role of the Stable Signal Peptide of the Arenavirus Envelope Glycoprotein in Membrane Fusion

The arenavirus envelope glycoprotein (GPC) retains a stable signal peptide (SSP) as an essential subunit in the mature complex. The 58-amino-acid residue SSP comprises two membrane-spanning hydrophobic regions separated by a short ectodomain loop that interacts with the G2 fusion subunit to promote...

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Detalhes bibliográficos
Main Authors: Messina, Emily L., York, Joanne, Nunberg, Jack H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372177/
https://ncbi.nlm.nih.gov/pubmed/22438561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.07241-11
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