Caricamento...

Prions, proteinase K and infectivity

It has been described that the breakdown of β-sheets in PrP(Sc) by denaturation results in loss of infectivity and PK-sensitivity, suggesting a relationship between the structure and PK-resistance. It is also known that an important fraction of total PrP(Sc) is PK-sensitive and can be isolated by th...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Sajnani, Gustavo, Requena, Jesús R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2012
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510858/
https://ncbi.nlm.nih.gov/pubmed/23044510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.22309
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !