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Detection and characterization of proteinase K-sensitive disease-related prion protein with thermolysin
Disease-related PrP(Sc) [pathogenic PrP (prion protein)] is classically distinguished from its normal cellular precursor, PrP(C)(cellular PrP) by its detergent insolubility and partial resistance to proteolysis. Although molecular diagnosis of prion disease has historically relied upon detection of...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Portland Press Ltd.
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2584334/ https://ncbi.nlm.nih.gov/pubmed/18684106 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20081235 |
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