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Direct Binding and Regulation of RhoA Protein by Cyclic GMP-dependent Protein Kinase Iα

Vascular smooth muscle cell (VSMC) tone is regulated by the state of myosin light chain (MLC) phosphorylation, which is in turn regulated by the balance between MLC kinase and MLC phosphatase (MLCP) activities. RhoA activates Rho kinase, which phosphorylates the regulatory subunit of MLC phosphatase...

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Detalhes bibliográficos
Main Authors: Kato, Mikio, Blanton, Robert, Wang, Guang-Rong, Judson, Timothy J., Abe, Yuich, Myoishi, Masafumi, Karas, Richard H., Mendelsohn, Michael E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510832/
https://ncbi.nlm.nih.gov/pubmed/23066013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.421040
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