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Association of 11β-Hydroxysteroid Dehydrogenase Type 1 Expression and Activity with Estrogen Receptor β in Adipose Tissue from Postmenopausal Women

OBJECTIVE: 11β-hydroxysteroid dehydrogenase type 1 (11βHSD1) regenerates active cortisol from inert cortisone in adipose tissue. Elevated adipose tissue 11βHSD1 activity is observed in obese humans and rodents where it is linked to obesity and its metabolic consequences. Menopause is also associated...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: McInnes, Kerry J, Andersson, Therése C, Šimonytė, Kotryna, Söderström, Ingegerd, Mattsson, Cecilia, Seckl, Jonathan R, Olsson, Tommy
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510652/
https://ncbi.nlm.nih.gov/pubmed/23190557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/gme.0b013e318258aad7
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