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Association of 11β-Hydroxysteroid Dehydrogenase Type 1 Expression and Activity with Estrogen Receptor β in Adipose Tissue from Postmenopausal Women

OBJECTIVE: 11β-hydroxysteroid dehydrogenase type 1 (11βHSD1) regenerates active cortisol from inert cortisone in adipose tissue. Elevated adipose tissue 11βHSD1 activity is observed in obese humans and rodents where it is linked to obesity and its metabolic consequences. Menopause is also associated...

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Detalhes bibliográficos
Main Authors: McInnes, Kerry J, Andersson, Therése C, Šimonytė, Kotryna, Söderström, Ingegerd, Mattsson, Cecilia, Seckl, Jonathan R, Olsson, Tommy
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510652/
https://ncbi.nlm.nih.gov/pubmed/23190557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/gme.0b013e318258aad7
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