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Identification of the ubiquitin ligase Triad1 as a regulator of endosomal transport
The ubiquitin system plays an important role in trafficking of signaling receptors from the plasma membrane to lysosomes. Triad1 is a ubiquitin ligase that catalyzes the formation of poly-ubiquitin chains linked via lysine-48 as well as lysine-63 residues. We show that depletion of Triad1 affects th...
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Main Authors: | , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Company of Biologists
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3509441/ https://ncbi.nlm.nih.gov/pubmed/23213454 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.2012778 |
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