Ubc13 and COOH Terminus of Hsp70-interacting Protein (CHIP) Are Required for Growth Hormone Receptor Endocytosis

Growth hormone receptor (GHR) endocytosis is a highly regulated process that depends on the binding and activity of the multimeric ubiquitin ligase, SCF(βTrCP) (Skp Cullin F-box). Despite a specific interaction between β-transducin repeat-containing protein (βTrCP) and the GHR, and a strict requirem...

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Detalhes bibliográficos
Main Authors: Slotman, Johan A., da Silva Almeida, Ana C., Hassink, Gerco C., van de Ven, Robert H. A., van Kerkhof, Peter, Kuiken, Hendrik J., Strous, Ger J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346074/
https://ncbi.nlm.nih.gov/pubmed/22433856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.302521
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