Sorting nexin 17 facilitates LRP recycling in the early endosome

The low-density lipoprotein (LDL) receptor-related protein (LRP) is a multiligand endocytic receptor and a member of the LDL receptor family. Here we show that sorting nexin 17 (Snx17) is part of the cellular sorting machinery that regulates cell surface levels of LRP by promoting its recycling. Whi...

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Detalhes bibliográficos
Main Authors: van Kerkhof, Peter, Lee, Jiyeon, McCormick, Lynn, Tetrault, Elena, Lu, Wenyan, Schoenfish, Marissa, Oorschot, Viola, Strous, Ger J, Klumperman, Judith, Bu, Guojun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2005
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1187941/
https://ncbi.nlm.nih.gov/pubmed/16052210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600756
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