Sorting nexin 17 facilitates LRP recycling in the early endosome

The low-density lipoprotein (LDL) receptor-related protein (LRP) is a multiligand endocytic receptor and a member of the LDL receptor family. Here we show that sorting nexin 17 (Snx17) is part of the cellular sorting machinery that regulates cell surface levels of LRP by promoting its recycling. Whi...

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Hlavní autoři: van Kerkhof, Peter, Lee, Jiyeon, McCormick, Lynn, Tetrault, Elena, Lu, Wenyan, Schoenfish, Marissa, Oorschot, Viola, Strous, Ger J, Klumperman, Judith, Bu, Guojun
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2005
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1187941/
https://ncbi.nlm.nih.gov/pubmed/16052210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600756
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