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Network rewiring is an important mechanism of gene essentiality change

Gene essentiality changes are crucial for organismal evolution. However, it is unclear how essentiality of orthologs varies across species. We investigated the underlying mechanism of gene essentiality changes between yeast and mouse based on the framework of network evolution and comparative genomi...

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Библиографические подробности
Главные авторы: Kim, Jinho, Kim, Inhae, Han, Seong Kyu, Bowie, James U., Kim, Sanguk
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3509348/
https://ncbi.nlm.nih.gov/pubmed/23198090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00900
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