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Network rewiring is an important mechanism of gene essentiality change

Gene essentiality changes are crucial for organismal evolution. However, it is unclear how essentiality of orthologs varies across species. We investigated the underlying mechanism of gene essentiality changes between yeast and mouse based on the framework of network evolution and comparative genomi...

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Bibliografski detalji
Glavni autori: Kim, Jinho, Kim, Inhae, Han, Seong Kyu, Bowie, James U., Kim, Sanguk
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3509348/
https://ncbi.nlm.nih.gov/pubmed/23198090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00900
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