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Network rewiring is an important mechanism of gene essentiality change

Gene essentiality changes are crucial for organismal evolution. However, it is unclear how essentiality of orthologs varies across species. We investigated the underlying mechanism of gene essentiality changes between yeast and mouse based on the framework of network evolution and comparative genomi...

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Detalhes bibliográficos
Main Authors: Kim, Jinho, Kim, Inhae, Han, Seong Kyu, Bowie, James U., Kim, Sanguk
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3509348/
https://ncbi.nlm.nih.gov/pubmed/23198090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00900
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