Kurarinone promotes TRAIL-induced apoptosis by inhibiting NF-κB-dependent cFLIP expression in HeLa cells

This study was designed to investigate the effects of the prenylated flavonoid kurarinone on TNF-related apoptosis inducing ligand (TRAIL)-induced apoptosis and its underlying mechanism. A low dose of kurarinone had no significant effect on apoptosis, but this compound markedly promoted tumor cell d...

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Detalhes bibliográficos
Main Authors: Seo, Ok-Won, Kim, Jung Hwan, Lee, Kwang-Soon, Lee, Kyu-Sun, Kim, Ji-Hee, Won, Moo-Ho, Ha, Kwon-Soo, Kwon, Young-Guen, Kim, Young-Myeong
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Society for Biochemistry and Molecular Biology 2012
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3509182/
https://ncbi.nlm.nih.gov/pubmed/22932446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3858/emm.2012.44.11.074
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