Genome-Scale Discovery of DNA-Methylation Biomarkers for Blood-Based Detection of Colorectal Cancer

BACKGROUND: There is an increasing demand for accurate biomarkers for early non-invasive colorectal cancer detection. We employed a genome-scale marker discovery method to identify and verify candidate DNA methylation biomarkers for blood-based detection of colorectal cancer. METHODOLOGY/PRINCIPAL F...

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Autori principali: Lange, Christopher P. E., Campan, Mihaela, Hinoue, Toshinori, Schmitz, Roderick F., van der Meulen-de Jong, Andrea E., Slingerland, Hilde, Kok, Peter J. M. J., van Dijk, Cornelis M., Weisenberger, Daniel J., Shen, Hui, Tollenaar, Robertus A. E. M., Laird, Peter W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3508917/
https://ncbi.nlm.nih.gov/pubmed/23209692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050266
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