Genome-scale analysis of aberrant DNA methylation in colorectal cancer

Colorectal cancer (CRC) is a heterogeneous disease in which unique subtypes are characterized by distinct genetic and epigenetic alterations. Here we performed comprehensive genome-scale DNA methylation profiling of 125 colorectal tumors and 29 adjacent normal tissues. We identified four DNA methyla...

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Detalhes bibliográficos
Main Authors: Hinoue, Toshinori, Weisenberger, Daniel J., Lange, Christopher P.E., Shen, Hui, Byun, Hyang-Min, Van Den Berg, David, Malik, Simeen, Pan, Fei, Noushmehr, Houtan, van Dijk, Cornelis M., Tollenaar, Rob A.E.M., Laird, Peter W.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266034/
https://ncbi.nlm.nih.gov/pubmed/21659424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.117523.110
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